Found 10 matching trials
Evaluation of the Effects of Urotensin-II and Soluble Epoxide Hydrolase Inhibitors on Skin Microvessel Tone in Patients With Heart Failure, and in Healthy Volunteers PHASE2 Urotensin II (U-II) is newly discovered protein that may play an important ...
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Evaluation of Soluble Epoxide Hydrolase (s-EH) Inhibitor in Patients With Mild to Moderate Hypertension and Impaired Glucose Tolerance PHASE2 The purpose of this study is to determine the safety and efficacy of AR9281...
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Arete Investigational site
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The Effect of Soluble Epoxide Hydrolase (SEH) on Depression N/A Depression is the most common mental disease and the second leading cause o...
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Nanfang Hospital, Southern Medical University
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Novel Soluble Epoxide Hydrolase Inhibitor for Neuropathic Pain in Patients With Spinal Cord Injury PHASE1 The goal of this clinical trial is to evaluate safety and tolerability of m...
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AU Medical Center
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A Study to Investigate the Safety and Pharmacokinetics of a Single Dose of GSK2256294 in Healthy Young Males and Elderly Subjects PHASE1 This study will investigate the safety and pharmacokinetics (PK) of a singl...
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GSK Investigational Site
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Safety, Tolerability and Exploratory Efficacy of EC5026 in Parkinson's Disease (STEP Study) PHASE1 The goal of this clinical trial is to learn if the oral drug candidate EC50...
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University of California Davis
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Subarachnoid Hemorrhage and Soluble Epoxide Hydrolase Inhibition Trial PHASE1 Soluble epoxide hydrolase (sEH) is the metabolizing enzyme of epoxyeicosatr...
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Oregon Health & Science University
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Soluble Epoxide Hydrolase Inhibition and Insulin Resistance PHASE2 The purpose of this study is to test how soluble epoxide hydrolase (sEH) in...
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Vanderbilt University Medical Center
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A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Doses of GSK2256294 in Healthy Volunteers, and Single and Repeat Doses of GSK2256294 in Adult Male Moderately Obese Smokers PHASE1 This study is the First Time in Human Study for GSK2256294 and will evaluat...
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GSK Investigational Site
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Cytochrome P450 Epoxygenase Pathway Regulation of Macrophage Function N/A Background:
Respiratory diseases affect more than 1 billion people worldwi...
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NIEHS, Research Triangle Park
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